What it is
Citrulline malate is citrulline bonded to malic acid. Malate is one of the steps in the cycle cells use to turn food into energy.
What it does in Memoclear
Two jobs in one. The citrulline half feeds the arginine and nitric oxide loop like the HCl form. The malate half enters the energy cycle and is involved in clearing ammonia and other waste that builds up when cells work hard, the kind of waste linked to a heavy-headed late afternoon. In Memoclear it is the second citrulline form, aimed at fatigue as much as flow.
Where it comes from in food
Citrulline from watermelon and cucumber; malate from apples and other tart fruit.
What the research says
Citrulline malate has been studied mainly for physical fatigue in exercise, with several trials reporting less soreness and slightly better endurance. The waste-clearing mechanism is plausible for mental fatigue but has not been tested directly for that.
Who should be careful
Well tolerated. Same nitric-oxide cautions as the other amino acids. Mild stomach upset at high doses in some people.
Where it sits in the Memoclear formula
L-Citrulline Malate works alongside L-Arginine (base), L-Arginine AKG 2:1 Extract, L-Citrulline HCl, Beta-Alanine, Niacin (Vitamin B3), Calcium (as calcium carbonate). Together the seven cover nitric oxide, cell energy and nerve signalling in one daily capsule.
Further reading
Citrulline malate and fatigue, PubMed. This research is on the ingredient, not on the finished Memoclear product.